A comprehensive account of the main classes of synthetic adjuvants, presenting the findings and experimental data needed to evaluate these substances for use in medicine and immunoregulation research. Classifies synthetic adjuvants according to chemical structure, namely: muramylpeptides, nucleic acid derivatives, sulfur-containing compounds, polymers, heterocyclic and aromatic compounds and lipids. Stressses the main pharmacological properties of adjuvants as well as their effects on nonspecific immune processes. Also reviews the potential use of adjuvants in clinical and veterinary applications.
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